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Fragile, unfaithful and persistent Ys—on how meiosis can shape sex chromosome evolution - Heredity

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Fragile, unfaithful and persistent Ys—on how meiosis can shape sex chromosome evolution - Heredity

Sex-linked inheritance is a stark exception to Mendel's Laws of Heredity. Here we discuss how the evolution of heteromorphic sex chromosomes (mainly the Y) has been shaped by the intricacies of the meiotic programme. We propose that persistence of Y chromosomes in distantly related mammalian phylogroups can be explained in the context of pseudoautosomal region (PAR) size, meiotic pairing strategies, and the presence of Y-borne executioner genes that regulate meiotic sex chromosome inactivation.

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Fragile, unfaithful and persistent Ys—on how meiosis can shape sex chromosome evolution - Heredity

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