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Combined IgE neutralization and Bifidobacterium longum supplementation reduces the allergic response in models of food allergy - Nature Communications
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IgE is central to the development of allergic diseases, and its neutralization alleviates allergic symptoms. However, most of these antibodies are based on IgG1, which is associated with an increased risk of fragment crystallizable-mediated side effects. Moreover, omalizumab, an anti-IgE antibody approved for therapeutic use, has limited benefits for patients with high IgE levels.
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