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Genetically encoded chemical crosslinking of carbohydrate - Nature Chemistry

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Genetically encoded chemical crosslinking of carbohydrate - Nature Chemistry

Protein–carbohydrate interactions play important roles in various biological processes, such as organism development, cancer metastasis, pathogen infection and immune response, but they remain challenging to study and exploit due to their low binding affinity and non-covalent nature. Here we site-specifically engineered covalent linkages between proteins and carbohydrates under biocompatible conditions.

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Genetically encoded chemical crosslinking of carbohydrate - Nature Chemistry

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Genetically encoded chemical crosslinking of carbohydrate - Nature Chemistry

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