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Blood monocyte-derived CD169+ macrophages contribute to antitumor immunity against glioblastoma - Nature Communications

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Blood monocyte-derived CD169+ macrophages contribute to antitumor immunity against glioblastoma - Nature Communications

Infiltrating tumor-associated macrophages (TAM) are known to impede immunotherapy against glioblastoma (GBM), however, TAMs are heterogeneous, and there are no clear markers to distinguish immunosuppressive and potentially immune-activating populations. Here we identify a subset of CD169+ macrophages promoting an anti-tumoral microenvironment in GBM. Using single-cell transcriptome analysis, we

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Blood monocyte-derived CD169+ macrophages contribute to antitumor immunity against glioblastoma - Nature Communications

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Blood monocyte-derived CD169+ macrophages contribute to antitumor immunity against glioblastoma - Nature Communications

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