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Bioengineering human intestinal mucosal grafts using patient-derived organoids, fibroblasts and scaffolds - Nature Protocols
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Tissue engineering is an interdisciplinary field that combines stem cells and matrices to form functional constructs that can be used to repair damaged tissues or regenerate whole organs. Tissue stem cells can be expanded and functionally differentiated to form 'mini-organs' resembling native tissue architecture and function. The choice of the scaffold is also pivotal to successful tissue reconstruction.
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