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Capturing the start point of the virus–cell interaction with high-speed 3D single-virus tracking - Nature Methods

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Capturing the start point of the virus–cell interaction with high-speed 3D single-virus tracking - Nature Methods

The early stages of the virus–cell interaction have long evaded observation by existing microscopy methods due to the rapid diffusion of virions in the extracellular space and the large three-dimensional cellular structures involved. Here we present an active-feedback single-particle tracking method with simultaneous volumetric imaging of the live cell environment called 3D-TrIm to address this knowledge gap.

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Capturing the start point of the virus–cell interaction with high-speed 3D single-virus tracking - Nature Methods

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Capturing the start point of the virus–cell interaction with high-speed 3D single-virus tracking - Nature Methods

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