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Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model - Cell Death & Disease

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Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model - Cell Death & Disease

Down syndrome (DS) is the most common chromosomal abnormality in live-born infants and is caused by trisomy of chromosome 21. Most individuals with DS display craniofacial dysmorphology, including reduced sizes of the skull, maxilla, and mandible. However, the underlying pathogenesis remains largely unknown.

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Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model - Cell Death & Disease

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Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model - Cell Death & Disease

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