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CD52 and OXPHOS—potential targets in ibrutinib-treated mantle cell lymphoma - Cell Death Discovery

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CD52 and OXPHOS—potential targets in ibrutinib-treated mantle cell lymphoma - Cell Death Discovery

Altered features of tumor cells acquired across therapy can result in the survival of treatment-resistant clones that may cause minimal residual disease (MRD). Despite the efficacy of ibrutinib in treating relapsed/refractory mantle cell lymphoma, the obstacle of residual cells contributes to relapses of this mature B-cell neoplasm, and the disease remains incurable.

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CD52 and OXPHOS—potential targets in ibrutinib-treated mantle cell lymphoma - Cell Death Discovery

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CD52 and OXPHOS—potential targets in ibrutinib-treated mantle cell lymphoma - Cell Death Discovery

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