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Humanized mouse models for immuno-oncology research - Nature Reviews Clinical Oncology

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Humanized mouse models for immuno-oncology research - Nature Reviews Clinical Oncology

Immunotherapy has emerged as a promising treatment paradigm for many malignancies and is transforming the drug development landscape. Although immunotherapeutic agents have demonstrated clinical efficacy, they are associated with variable clinical responses, and substantial gaps remain in our understanding of their mechanisms of action and specific biomarkers of response.

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Humanized mouse models for immuno-oncology research - Nature Reviews Clinical Oncology

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Humanized mouse models for immuno-oncology research - Nature Reviews Clinical Oncology

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