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RBM4 regulates cellular senescence via miR1244/SERPINE1 axis - Cell Death & Disease

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RBM4 regulates cellular senescence via miR1244/SERPINE1 axis - Cell Death & Disease

Cellular senescence serves as a powerful tumor suppressing mechanism that inhibits the proliferation of cancer cells bearing oncogenic mutations at the initial stage of cancer development. RNA-binding proteins (RBPs) play important roles in cancer progression and treatment through distinct functions. However, functions and mechanisms of RNA binding proteins in regulating senescence remain elusive. Here we reported that the RNA binding protein RBM4 contributed to cellular senescence.

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RBM4 regulates cellular senescence via miR1244/SERPINE1 axis - Cell Death & Disease

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RBM4 regulates cellular senescence via miR1244/SERPINE1 axis - Cell Death & Disease

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Unlocking the Power of Knowledge
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Unlocking the Power of Knowledge
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