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Simultaneous sequencing of genetic and epigenetic bases in DNA - Nature Biotechnology

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Simultaneous sequencing of genetic and epigenetic bases in DNA - Nature Biotechnology

DNA comprises molecular information stored in genetic and epigenetic bases, both of which are vital to our understanding of biology. Most DNA sequencing approaches address either genetics or epigenetics and thus capture incomplete information. Methods widely used to detect epigenetic DNA bases fail to capture common C-to-T mutations or distinguish 5-methylcytosine from 5-hydroxymethylcytosine.

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Simultaneous sequencing of genetic and epigenetic bases in DNA - Nature Biotechnology

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Simultaneous sequencing of genetic and epigenetic bases in DNA - Nature Biotechnology

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