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Predicting the prevalence of complex genetic diseases from individual genotype profiles using capsule networks - Nature Machine Intelligence

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Predicting the prevalence of complex genetic diseases from individual genotype profiles using capsule networks - Nature Machine Intelligence

Diseases that have a complex genetic architecture tend to suffer from considerable amounts of genetic variants that, although playing a role in the disease, have not yet been revealed as such. Two major causes for this phenomenon are genetic variants that do not stack up effects, but interact in complex ways; in addition, as recently suggested, the omnigenic model postulates that variants interact in a holistic manner to establish disease phenotypes.

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Predicting the prevalence of complex genetic diseases from individual genotype profiles using capsule networks - Nature Machine Intelligence

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Predicting the prevalence of complex genetic diseases from individual genotype profiles using capsule networks - Nature Machine Intelligence

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