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PFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages - Nature Metabolism

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PFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages - Nature Metabolism

Resolving-type macrophages prevent chronic inflammation by clearing apoptotic cells through efferocytosis. These macrophages are thought to rely mainly on oxidative phosphorylation, but emerging evidence suggests a possible link between efferocytosis and glycolysis. To gain further insight into this issue, we investigated molecular–cellular mechanisms involved in efferocytosis-induced macrophage glycolysis and its consequences.

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PFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages - Nature Metabolism

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PFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages - Nature Metabolism

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