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Master kinases extracted from proteogenomic networks in glioblastoma drive cancer subtypes - Nature Cancer

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Master kinases extracted from proteogenomic networks in glioblastoma drive cancer subtypes - Nature Cancer

Using an unbiased algorithm based on kinase–phosphorylation site interactions that is applicable to any proteomic dataset, we identified and experimentally validated two protein kinases (PKCδ and DNA-PKcs) as the master kinases that drive two functional subtypes of glioblastoma multiforme and are potential therapeutic targets of other cancer subtypes.

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Master kinases extracted from proteogenomic networks in glioblastoma drive cancer subtypes - Nature Cancer

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Master kinases extracted from proteogenomic networks in glioblastoma drive cancer subtypes - Nature Cancer

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