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Cryo-electron tomography on focused ion beam lamellae transforms structural cell biology - Nature Methods

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Cryo-electron tomography on focused ion beam lamellae transforms structural cell biology - Nature Methods

Cryogenic electron microscopy and data processing enable the determination of structures of isolated macromolecules to near-atomic resolution. However, these data do not provide structural information in the cellular environment where macromolecules perform their native functions, and vital molecular interactions can be lost during the isolation process.

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Cryo-electron tomography on focused ion beam lamellae transforms structural cell biology - Nature Methods

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Cryo-electron tomography on focused ion beam lamellae transforms structural cell biology - Nature Methods

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