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Catalytic asymmetric synthesis of cannabinoids and menthol from neral - Nature

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Catalytic asymmetric synthesis of cannabinoids and menthol from neral - Nature

The selective conversion of natural or synthetic neral to (1R,6S)-trans-isopiperitenol would enable and expedite sustainable routes to menthol1,2 and cannabinoids3–5. However, this reaction has been considered impossible because its product is more reactive to the required acid catalysts than its starting material, resulting in several side products6–9.

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Catalytic asymmetric synthesis of cannabinoids and menthol from neral - Nature

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Catalytic asymmetric synthesis of cannabinoids and menthol from neral - Nature

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