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Peroxisome biogenesis initiated by protein phase separation - Nature

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Peroxisome biogenesis initiated by protein phase separation - Nature

Peroxisomes are organelles that carry out β-oxidation of fatty acids and amino acids. Both rare and prevalent diseases are caused by their dysfunction1. Among disease-causing variant genes are those required for protein transport into peroxisomes. The peroxisomal protein import machinery, which also shares similarities with chloroplasts2, is unique in transporting folded and large, up to 10 nm in diameter, protein complexes into peroxisomes3.

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Peroxisome biogenesis initiated by protein phase separation - Nature

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Peroxisome biogenesis initiated by protein phase separation - Nature

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