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Metabolic landscape of the male mouse gut identifies different niches determined by microbial activities - Nature Metabolism

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Metabolic landscape of the male mouse gut identifies different niches determined by microbial activities - Nature Metabolism

Distinct niches of the mammalian gut are populated by diverse microbiota, but the contribution of spatial variation to intestinal metabolism remains unclear. Here we present a map of the longitudinal metabolome along the gut of healthy colonized and germ-free male mice. With this map, we reveal a general shift from amino acids in the small intestine to organic acids, vitamins and nucleotides in the large intestine.

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Metabolic landscape of the male mouse gut identifies different niches determined by microbial activities - Nature Metabolism

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Metabolic landscape of the male mouse gut identifies different niches determined by microbial activities - Nature Metabolism

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