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A large screen identifies beta-lactam antibiotics which can be repurposed to target the syphilis agent - npj Antimicrobials and Resistance

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A large screen identifies beta-lactam antibiotics which can be repurposed to target the syphilis agent - npj Antimicrobials and Resistance

Syphilis, caused by the spirochete Treponema pallidum subsp. pallidum (hereafter called T. pallidum), is re-emerging as a worldwide sexually transmitted infection. A single intramuscular dose of benzathine penicillin G is the preferred syphilis treatment option. Both supply shortage concerns and the potential for acquired antibiotic resistance further the need to broaden the repertoire of syphilis therapeutics.

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A large screen identifies beta-lactam antibiotics which can be repurposed to target the syphilis agent - npj Antimicrobials and Resistance

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A large screen identifies beta-lactam antibiotics which can be repurposed to target the syphilis agent - npj Antimicrobials and Resistance

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