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11 months ago

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Tetracenomycin X sequesters peptidyl-tRNA during translation of QK motifs - Nature Chemical Biology

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Tetracenomycin X sequesters peptidyl-tRNA during translation of QK motifs - Nature Chemical Biology

As antimicrobial resistance threatens our ability to treat common bacterial infections, new antibiotics with limited cross-resistance are urgently needed. In this regard, natural products that target the bacterial ribosome have the potential to be developed into potent drugs through structure-guided design, provided their mechanisms of action are well understood.

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Tetracenomycin X sequesters peptidyl-tRNA during translation of QK motifs - Nature Chemical Biology

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Tetracenomycin X sequesters peptidyl-tRNA during translation of QK motifs - Nature Chemical Biology

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