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Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium - Nature Nanotechnology

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Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium - Nature Nanotechnology

The therapeutic potential of liposomes to deliver drugs into inflamed tissue is well documented. Liposomes are believed to largely transport drugs into inflamed joints by selective extravasation through endothelial gaps at the inflammatory sites, known as the enhanced permeation and retention effect. However, the potential of blood-circulating myeloid cells for the uptake and delivery of liposomes has been largely overlooked.

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Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium - Nature Nanotechnology

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Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium - Nature Nanotechnology

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