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DBlink: dynamic localization microscopy in super spatiotemporal resolution via deep learning - Nature Methods

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DBlink: dynamic localization microscopy in super spatiotemporal resolution via deep learning - Nature Methods

Single-molecule localization microscopy (SMLM) has revolutionized biological imaging, improving the spatial resolution of traditional microscopes by an order of magnitude. However, SMLM techniques require long acquisition times, typically a few minutes, to yield a single super-resolved image, because they depend on accumulation of many localizations over thousands of recorded frames. Hence, the capability of SMLM to observe dynamics at high temporal resolution has always been limited.

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DBlink: dynamic localization microscopy in super spatiotemporal resolution via deep learning - Nature Methods

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DBlink: dynamic localization microscopy in super spatiotemporal resolution via deep learning - Nature Methods

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