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A synthetic metastatic niche reveals antitumor neutrophils drive breast cancer metastatic dormancy in the lungs - Nature Communications

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A synthetic metastatic niche reveals antitumor neutrophils drive breast cancer metastatic dormancy in the lungs - Nature Communications

Biomaterial scaffolds mimicking the environment in metastatic organs can deconstruct complex signals and facilitate the study of cancer progression and metastasis. Here we report that a subcutaneous scaffold implant in mouse models of metastatic breast cancer in female mice recruits lung-tropic circulating tumor cells yet suppresses their growth through potent in situ antitumor immunity.

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A synthetic metastatic niche reveals antitumor neutrophils drive breast cancer metastatic dormancy in the lungs - Nature Communications

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A synthetic metastatic niche reveals antitumor neutrophils drive breast cancer metastatic dormancy in the lungs - Nature Communications

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