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Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustion - Nature Immunology

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Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustion - Nature Immunology

Persistent exposure to antigen during chronic infection or cancer renders T cells dysfunctional. The molecular mechanisms regulating this state of exhaustion are thought to be common in infection and cancer, despite obvious differences in their microenvironments.

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Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustion - Nature Immunology

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Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustion - Nature Immunology

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