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Cell-free DNA methylome analysis for early preeclampsia prediction - Nature Medicine

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Cell-free DNA methylome analysis for early preeclampsia prediction - Nature Medicine

Preeclampsia (PE) is a leading cause for peripartal morbidity, especially if developing early in gestation. To enable prophylaxis in the prevention of PE, pregnancies at risk of PE must be identified early—in the first trimester. To identify at-risk pregnancies we profiled methylomes of plasma-derived, cell-free DNA from 498 pregnant women, of whom about one-third developed early-onset PE.

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Cell-free DNA methylome analysis for early preeclampsia prediction - Nature Medicine

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Cell-free DNA methylome analysis for early preeclampsia prediction - Nature Medicine

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