@curator

8 months ago

Article

Elongation roadblocks mediated by dCas9 across human genes modulate transcription and nascent RNA processing - Nature Structural & Molecular Biology

Rating: 0.0

Likes: 1

Library: 1

Elongation roadblocks mediated by dCas9 across human genes modulate transcription and nascent RNA processing - Nature Structural & Molecular Biology

Non-cleaving Cas9 (dCas9) is widely employed to manipulate specific gene loci, often with scant regard for unintended transcriptional effects. We demonstrate here that dCas9 mediates precise RNA polymerase II transcriptional pausing followed by transcription termination and potential alternative polyadenylation. By contrast, alternative splicing is unaffected, likely requiring more sustained alteration to elongation speed.

Rate This Post

Rate The Educational Value

Rate The Ease of Understanding and Presentation

Interesting or Boring? Rate the Entertainment Value

Related Topics

technology elongation gene transcription rna processing

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Add articles, eBooks or videos to your Library.
You can revisit, watch or read your favorite items later

Learning is Fun!

Close

Unlocking the Power of Knowledge
for Humanity's Progress

By harnessing the power of Artificial Intelligence, Boostlane is changing the way we engage with information, connect with experts, and foster personal growth.

Explore Topics,
Discover Ideas,
Share knowledge,
Learn from Experts

Boostlane is a media platform that aims to revolutionize how we research, discover, and learn about our favorite topics

Boostlane relies on the power of Artificial Intelligence and a Community of Researchers to curate and deliver reliable, insightful, and purposeful knowledge

Support a platform focused on research and useful knowledge.
Create personalized feeds.
Follow your favorite topics and learn something new every day.
Learn with the assistance of people and Artificial Intelligence Systems.
Use innovative features designed to organize information and foster personal growth.
Collect your favorite media in your private Library.

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Unlocking the Power of Knowledge
for Humanity's Progress

By harnessing the power of Artificial Intelligence, Boostlane is changing the way we engage with information, connect with experts, and foster personal growth.

Explore Topics,
Discover Ideas,
Share knowledge,
Learn from Experts

Boostlane is a media platform that aims to revolutionize how we research, discover, and learn about our favorite topics

Boostlane relies on the power of Artificial Intelligence and a Community of Researchers to curate and deliver reliable, insightful, and purposeful knowledge

Support a platform focused on research and useful knowledge.
Create personalized feeds.
Follow your favorite topics and learn something new every day.
Learn with the assistance of people and Artificial Intelligence Systems.
Use innovative features designed to organize information and foster personal growth.
Collect your favorite media in your private Library.

Elongation roadblocks mediated by dCas9 across human genes modulate transcription and nascent RNA processing - Nature Structural & Molecular Biology

Rate This Post

Related Topics

Comments

Media:

My Account:

Boostlane:

Select a Category

Topics Trending Today

Recommended Media

Boostlane Reward System

Unlocking the Power of Knowledge
for Humanity's Progress

Quick Links

Select a Locale

Unlocking the Power of Knowledge
for Humanity's Progress

Elongation roadblocks mediated by dCas9 across human genes modulate transcription and nascent RNA processing - Nature Structural & Molecular Biology

Rate This Post

Related Topics

Comments

Media:

My Account:

Boostlane:

Select a Category

Topics Trending Today

Recommended Media

Boostlane Reward System

Unlocking the Power of Knowledge for Humanity's Progress

Quick Links

Select a Locale

Unlocking the Power of Knowledge for Humanity's Progress

Unlocking the Power of Knowledge
for Humanity's Progress

Unlocking the Power of Knowledge
for Humanity's Progress