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Scalable single-cell profiling of chromatin modifications with sciCUT&Tag - Nature Protocols
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Cleavage under targets and tagmentation (CUT&Tag) is an antibody-directed in situ chromatin profiling strategy that is rapidly replacing immune precipitation-based methods, such as chromatin immunoprecipitation–sequencing. The efficiency of the method enables chromatin profiling in single cells but is limited by the numbers of cells that can be profiled.
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