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O-GlcNAcylation determines the translational regulation and phase separation of YTHDF proteins - Nature Cell Biology

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O-GlcNAcylation determines the translational regulation and phase separation of YTHDF proteins - Nature Cell Biology

N6-methyladenosine (m6A) is the most abundant internal mRNA nucleotide modification in mammals, regulating critical aspects of cell physiology and differentiation. The YTHDF proteins are the primary readers of m6A modifications and exert physiological functions of m6A in the cytosol. Elucidating the regulatory mechanisms of YTHDF proteins is critical to understanding m6A biology.

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O-GlcNAcylation determines the translational regulation and phase separation of YTHDF proteins - Nature Cell Biology

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O-GlcNAcylation determines the translational regulation and phase separation of YTHDF proteins - Nature Cell Biology

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