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Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons - Nature Biotechnology

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Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons - Nature Biotechnology

The maturation of human pluripotent stem cell (hPSC)-derived neurons mimics the protracted timing of human brain development, extending over months to years for reaching adult-like function. Prolonged in vitro maturation presents a major challenge to stem cell-based applications in modeling and treating neurological disease.

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Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons - Nature Biotechnology

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Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons - Nature Biotechnology

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