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TRGT-ing the dark genome to accurately characterize tandem repeats at scale - Nature Biotechnology

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TRGT-ing the dark genome to accurately characterize tandem repeats at scale - Nature Biotechnology

Repetitive DNA sequences known as tandem repeats (TRs) are linked to dozens of monogenic diseases and to cancer. We developed a computational method to characterize TRs using PacBio HiFi sequencing. This software can be used to discover and profile pathogenic repeat expansions and to catalog genetic and epigenetic variation in TR regions.

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TRGT-ing the dark genome to accurately characterize tandem repeats at scale - Nature Biotechnology

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TRGT-ing the dark genome to accurately characterize tandem repeats at scale - Nature Biotechnology

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