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Organocatalytic olefin C–H functionalization for enantioselective synthesis of atropisomeric 1,3-dienes - Nature Catalysis

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Organocatalytic olefin C–H functionalization for enantioselective synthesis of atropisomeric 1,3-dienes - Nature Catalysis

The availability of structurally and stereochemically diverse chemical scaffolds is important to support continual development of drug discovery, functional materials and asymmetric synthesis. Axially chiral 1,3-dienes, particularly acyclic ones, are potentially valuable yet underutilized skeletons due to concerns about chiral stability and the absence of suitable synthetic conditions.

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Organocatalytic olefin C–H functionalization for enantioselective synthesis of atropisomeric 1,3-dienes - Nature Catalysis

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Organocatalytic olefin C–H functionalization for enantioselective synthesis of atropisomeric 1,3-dienes - Nature Catalysis

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