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Targeting ferroptosis opens new avenues for the development of novel therapeutics - Signal Transduction and Targeted Therapy

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Targeting ferroptosis opens new avenues for the development of novel therapeutics - Signal Transduction and Targeted Therapy

Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics, including altered iron homeostasis, reduced defense against oxidative stress, and abnormal lipid peroxidation. Recent studies have provided compelling evidence supporting the notion that ferroptosis plays a key pathogenic role in many diseases such as various cancer types, neurodegenerative disease, diseases involving tissue and/or organ injury, and inflammatory and infectious diseases.

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Targeting ferroptosis opens new avenues for the development of novel therapeutics - Signal Transduction and Targeted Therapy

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Targeting ferroptosis opens new avenues for the development of novel therapeutics - Signal Transduction and Targeted Therapy

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