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Essential transcription factors for induced neuron differentiation - Nature Communications

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Essential transcription factors for induced neuron differentiation - Nature Communications

Neurogenins are proneural transcription factors required to specify neuronal identity. Their overexpression in human pluripotent stem cells rapidly produces cortical-like neurons with spiking activity and, because of this, they have been widely adopted for human neuron disease models. However, we do not fully understand the key downstream regulatory effectors responsible for driving neural differentiation.

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Essential transcription factors for induced neuron differentiation - Nature Communications

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Essential transcription factors for induced neuron differentiation - Nature Communications

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