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WIPI4 loss linked to ferroptosis - Nature Cell Biology

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WIPI4 loss linked to ferroptosis - Nature Cell Biology

β-propeller protein-associated neurodegeneration (BPAN) is caused by loss of functional WIPI4. A new study reports that depletion of WIPI4 induces ferroptosis via changes in mitochondrial membrane lipids, independently of the role of WIPI4 in autophagy, providing insights into the cause of neurodegeneration in BPAN.

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WIPI4 loss linked to ferroptosis - Nature Cell Biology

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WIPI4 loss linked to ferroptosis - Nature Cell Biology

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