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High-density volumetric super-resolution microscopy - Nature Communications

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High-density volumetric super-resolution microscopy - Nature Communications

Volumetric super-resolution microscopy typically encodes the 3D position of single-molecule fluorescence into a 2D image by changing the shape of the point spread function (PSF) as a function of depth. However, the resulting large and complex PSF spatial footprints reduce biological throughput and applicability by requiring lower labeling densities to avoid overlapping fluorescent signals.

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High-density volumetric super-resolution microscopy - Nature Communications

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High-density volumetric super-resolution microscopy - Nature Communications

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