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Tying the knot with lysine - Nature Reviews Chemistry

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Tying the knot with lysine - Nature Reviews Chemistry

Targeted covalent inhibitors (TCIs) can react irreversibly with lysine in kinases and other proteins. Small molecule TCIs can have both broad or specific lysine targeting whereas peptide- and protein-based TCIs were shown to provide high target specificity for lysines in shallow protein surfaces.

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Tying the knot with lysine - Nature Reviews Chemistry

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