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A negative feedback loop between TET2 and leptin in adipocyte regulates body weight - Nature Communications

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A negative feedback loop between TET2 and leptin in adipocyte regulates body weight - Nature Communications

Ten-eleven translocation (TET) 2 is an enzyme that catalyzes DNA demethylation to regulate gene expression by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine, functioning as an essential epigenetic regulator in various biological processes. However, the regulation and function of TET2 in adipocytes during obesity are poorly understood.

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A negative feedback loop between TET2 and leptin in adipocyte regulates body weight - Nature Communications

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A negative feedback loop between TET2 and leptin in adipocyte regulates body weight - Nature Communications

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